Alga’Digest - Smart Algae Cultivation for Functional Food Applications: Enhancing β-Glucan and Nutrient Bioaccessibility
Summary
Food Biotechnology
Public, Fribourg Agri & Food
Agroscope
Frewitt
Spir’it Naturae
Carmen Jungo Rhême
Skills directory
March 2026 - February 2027
The aim of this project is to develop sustainable, high-value functional food ingredients from microalgae by combining optimized cultivation conditions and advanced cell disruption.
Alga’Digest project aims to develop a sustainable method for producing functional ingredients from microalgae for food applications. The project combines autotrophic cultivation, a process in which microalgae use light energy and inorganic substances, like carbon dioxide and minerals, to produce their own food ,without relying on organic matter, with phosphate limitation to enhance β-glucans and other essential nutrients.
To maximize the nutritional value and bioaccessibility of algae-derived compounds, AlgaDigest integrates advanced cell disruption processes and in vitro digestion tests. A key innovation is the use of Frewitt’s NanoWitt technology, which enables efficient cell lysis with minimal heat generation, preserving sensitive bioactive compounds.
Preliminary tests by Frewitt and Agroscope in 2025, confirmed NanoWitt’s potential for microalgae cell lysis. Building on these results, the project includes a comparative study of Arthrospira platensis and Chlorella vulgaris microalgae. To ensure industrial relevance, the project also includes large-scale cultivation at Spir’it Naturae.
The partners aim to bridge the gap between laboratory innovation and market-ready solutions, contributing to healthier and sustainable food and regional economic development.